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BPS BPS-Pharmacotherapy Exam Syllabus Topics:
| Section | Weight | Objectives |
|---|---|---|
| Topic 1: Drug Information and Evidence-Based Medicine | 25% | - Literature Evaluation
|
| Topic 2: Patient-Centered Pharmacotherapy | 55% | - Monitoring and Follow-Up
|
| Topic 3: System-Based Standards and Population-Based Pharmacotherapy | 20% | - Medication-Use Systems
|
BPS Pharmacotherapy (Part1 and Part2) Sample Questions:
Question 1
A pharmacotherapy specialist is conducting a pharmacokinetic study of a drug. The pharmacokinetic profile of this drug is best described by a one-compartment model with a mean elimination rate constant of 0.173/h. The standard curve for the assay to be used covers the range of 5-40mcg/mL. Samples are collected shortly after single intravenous bolus drug administration, and at 4 and 8 hours after dosing. Preliminary analysis shows that the 4-hour sample concentration is 25 mcg/mL. In this situation, which of the following statements is correct?
A. Both the initial and 8-hour concentration points are probably outside the range of the standard curve and cannot be reliably measured without diluting the samples.
B. The initial plasma concentration is probably outside the range of the standard curve' it may be possible to dilute the sample and re-assay.
C. Both the initial and 8-hour concentration points are probably outside the range of the standard curve but can be reliably quantitated by extrapolating the curve to higher and lower points.
D. All plasma concentrations are probably within the range of the standard curve and can be reliably measured.
Question 2
When low molecular weight heparin is prescribed, in which of the following patient populations would monitoring anti-factor-Xa levels be reasonable to consider?
A. Protein C and Protein S deficiencies
B. Anticardiolipin antibody syndrome
C. Past history of GI bleeding
D. Significant renal impairment
Question 3
A physician suspects that a patient's symptoms are related to abrupt discontinuation of a certain drug and asks the pharmacotherapy specialist about common reactions in this type of situation.
A literature search produces one case report of a discontinuation syndrome involving the drug.
What is the most appropriate action to take with regard to the current suspected adverse event?
A. Write and submit a case report detailing the event.
B. Report the event to the FDA MedWatch program.
C. Complete a manufacturer's adverse event report.
D. Report the event to the P & T Committee.
Question 4
Which of the following is the best initial strategy in addition to docusate sodium to prevent constipation in a 45-year-old patient initiating around-the-clock morphine therapy for chronic pain associated with malignancy?
A. Psyllium
B. Glycerin suppository
C. Senna
D. Magnesium citrate
Question 5
A 14-year-old boy has mild papulopustular acne on the forehead, the nose, and the cheeks, with sparse involvement of the upper trunk and the neck. Which of the following is the most appropriate initial therapeutic agent?
A. Topical erythromycin
B. Topical isotretinoin
C. Oral tretinoin
D. Topical benzoyl peroxide
Solutions:
| Question 1 Answer: D | Question 2 Answer: B | Question 3 Answer: A | Question 4 Answer: C | Question 5 Answer: B |
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